As a national intangible cultural heritage project, the research on the Pizhou paper-molded lion head focuses on exploring the cultural connotations, craftsmanship features and modern inheritance predicaments of this regional traditional handicraft, aiming to provide theoretical references and practical paths for the protection and innovation of folk arts. From the perspectives of history, anthropology and design, its production techniques, form characteristics and ethical evolution are analyzed. By comparing the artistic features of lions in the north and south, the logic of integration and innovation in the shape, decoration and color of the Pizhou paper-molded lion head is analyzed, and the semiotic theory is applied to explain its cultural symbol system. The formation of the Pizhou paper-molded lion head is influenced by its geographical hub position and the cultural integration of the north and south. Its craftsmanship system is characterized by natural materials and seven core procedures, combining environmental protection concepts and artistic values. In terms of form, it combines the robustness of northern lions with the delicacy of southern lions, and builds a unique visual language through the outline, facial features and decorative patterns. In the process of modern transformation, although it faces challenges such as the loss of inheritance subjects and inefficient production models, it has achieved creative transformation through the synergy of traditional genes and modern design, relying on the support of intangible cultural heritage policies and the exploration of cultural values. It has deeply integrated into modern life while maintaining its authenticity, becoming a carrier to activate regional cultural identity.